Fig. 1

CQA attenuated high fat diet (HFD)-induced obesity (DIO) and metabolic disorders in mice. The mice were fed a HFD for 8 weeks and then orally treated with vehicle or CQA (150 mg/kg) daily for another 8 weeks. a Body weight. b Lean mass. c Fat mass. d Fat/lean index. e Glucose tolerance test (GTT) and area under the curve (AUC). f Insulin tolerance test (ITT) and AUC. g Fasting blood glucose (FBG). h Fasting insulin. i Insulin resistance (HOMA-IR) index. j Serum triglyceride. k Serum total cholesterol (T-CHO). l Serum high-density lipoprotein cholesterol (HDL-C). m Serum low-density lipoprotein cholesterol (LDL-C). n Liver weight. o Hepatic triglyceride. p Hepatic T-CHO. q Representative H&E staining (upper) and Oil red O staining (lower) of liver sections, scale bar: 50 μm. Lipids were stained positive (red color) with Oil red O and quantified by Image J software. LFD, n = 6/group. HFD-V and HFD-CQA, n = 8/group. Data are presented as mean ± SD. *p < 0.05; **p < 0.01; and ***p < 0.001 versus HFD-V