Fig. 4
From: Multi-omic interactions in the gut of children at the onset of islet autoimmunity
The microbiome and metaproteome are associated with islet autoimmunity. Linear mixed models identified A Ruminococceceae otu194951 associated with case/control status overall and B Ruminococceceae otu591734 associated with case/control status dependent on timepoint. C Proteins associated with case-control designation and D proteins associated with case/control status dependent on timepoint. Case pre: IAb+ subjects prior to seroconversion, case post: IAb+ subjects after seroconversion, control pre: IAb− subjects at first timepoint, control post: IAb− subjects at second timepoint