Fig. 2
From: Multi-omic interactions in the gut of children at the onset of islet autoimmunity
Dynamics of the metaproteome during early childhood. A The number of human proteins, non-human proteins, immunoglobulin-variable regions detected, and the proportion of immunoglobulin (IG)-variable regions among total protein intensity. For each panel, the thick blue curve represents all samples, the grey shaded are represents the 95% confidence interval, and the thinner curves represent each sample group. B PCA of the metaproteome shows PC1 and PC2 with contributing human proteins labeled individually. Genus of microbial proteins identified in each quadrant are indicated. C The correlation of the first 5 principal components with metrics from amplicon sequencing (phylum abundance, observed, Shannon) and metaproteomics (n human proteins, n non-human proteins). *p < 0.05, **p < 0.01, ***p < 0.001