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Fig. 2 | Microbiome

Fig. 2

From: Human microbiota drives hospital-associated antimicrobial resistance dissemination in the urban environment and mirrors patient case rates

Fig. 2

Dissemination of antimicrobial resistance (AMR) genes correlates with the presence of human bacteria. A Linear regression showing a positive and significant correlation (R = 0.67, p-value = 1.3e−6) between the relative abundance of human-associated bacterial species and the abundance of AMR genes. B Boxplots showing the relative abundance of ARGs in the three metagenomic clusters. C Non-metric multidimensional scaling (NMDS) analysis based on the abundance of AMR genes in all samples. Samples are colored by clusters. Variation in the horizontal axis (NMDS1) explains the separation of samples according to clusters based on their AMR gene repertory and abundance. D Barplot ranking antibiotic resistance gene classes that mostly contribute to the separation between samples observed in NMDS1 of panel B. Resistance to beta-lactams is the most contributing feature to separation of samples in the three predefined clusters. E Boxplot showing the alpha diversity (measured as the Shannon index) of beta-lactam resistance genes according to clusters. Level of statistical significance is shown as asterisks (p < 0.01)

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Microbiome

ISSN: 2049-2618

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