Fig. 3
From: Vaginal microbiome-host interactions modeled in a human vagina-on-a-chip
D-lactate production in vagina chip. A D-lactate and L-lactate levels measured in the effluent of the epithelial channel of vagina chip cultured in the absence (control) or presence single strain (C0006A1) or multi-strain (OC1, OC2, OC3) L. crispatus consortia at 72 h post-inoculation. Each data point indicates one chip; data are presented as median with 95% CI. Significance was calculated by one-way ANOVA; *, P < 0.05 vs. control, #, P < 0.05 vs. OC1, ¥, P < 0.05 vs. C0006A1. B Table showing median D-lactate concentrations (mM) measured in the vagina of women with Lactobacillus-dominated communities compared to concentrations measured in vagina chips cultured with different L. crispatus consortia (OC1, OC2, OC3) and the C0006A1 strain