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Fig. 2 | Microbiome

Fig. 2

From: Bifidobacterium animalis subsp. lactis Probio-M8 undergoes host adaptive evolution by glcU mutation and translocates to the infant’s gut via oral-/entero-mammary routes through lactation

Fig. 2

Phylogenetic tree constructed based on the core genes of 266 genomes of Bifidobacterium animalis subsp. lactis. The tree was built by the maximum likelihood method using DNA sequences of 1271 core genes of 266 genomes with 1000 bootstrap iterations. The 266 genomes included 16 metagenome-assembled genomes (MAGs; prefixed with ‘meta’ and written in brown), 222 isolates of mother-infant pairs (written in black), 24 isolates from M8 dry powder (written in blue), and four reference strains, including M8, BB-12, V9, and DSM 10140T (written in green). The phylogenetic tree was separated into a big (red) and a small (black) branches. Isolates in the big (red) branch were phylogenetically inseparable, including 13 MAGs, 195 isolates from mother-infant pairs, all 24 isolates from M8 dry powder, and M8. The small branch comprised three MAGs, 27 isolates from mother-infant pairs, and genomes of BB-12, V9, and DSM 10140T

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Microbiome

ISSN: 2049-2618

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