Fig. 6

Integrative metabolic view in the rumen and colon of sika deer between birth and postweaning. Histogram showing the significantly enriched pathways in rumen (a) and colon (b). Pathway enrichment analysis was performed by a one-side Fisher test based on the significantly increased KOs (full results were supplied in Table S6). The significance of KOs was determined by a Benjamini-Hochberg-adjusted P-value < 0.05 based on the relative abundance between day 70 vs day 1. The x-axis represents the gene sets in each pathway. The graphs of the metabolic pathways of carbohydrate and amino acids in rumen (c) and colon (d). The light green and light blue backgrounds represent the metabolism of carbohydrate and amino acids, respectively. The rounded rectangle and ellipse indicate metabolites associated with carbohydrate and amino acids, respectively. Red- and brown-rounded rectangle/ellipse indicate the significantly increased/increased, while blue and gray rectangle/ellipse indicate the significantly decreased/decreased. The significant increase of enzyme codes and gene names between day 70 vs day 1 in the pathways was indicated as red text. P, phosphate; PEP, phosphoenolpyruvate; G3P, glycerol 3-phosphate; Tyr, tyrosine; Phe, phenylalanine; Ser, serine; Cys, cysteine; Thr, threonine; Ile, isoleucine; Asp, aspartate; Met, methionine; Lys, lysine; Gly, glycine; Pro, proline; and Arg, arginine