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Fig. 2 | Microbiome

Fig. 2

From: Enterotypical Prevotella and three novel bacterial biomarkers in preoperative stool predict the clinical outcome of colorectal cancer

Fig. 2

Screening prognostic microbial biomarkers. A PFS curve by enterotype. Integers 1 and 2 indicate Bacteroides-enriched enterotype 1 and Prevotella-enriched enterotype 2, respectively. B OS curve by enterotype. C PFS curve by the dichotomized relative abundance of Prevotella. D OS curve by the dichotomized relative abundance of Prevotella. E Schematic description for the screening of prognostic bacterial species. Dichotomized bacterial abundance is applied to both univariate log-rank test and multivariate Cox proportional hazard model. The entire data and random subsamples were used for biomarker screening. F–I PFS curves by the presence of Bacteroides sp. (F), Fusobacterium nucleatum (G), Dialister invisus (H), and Pyramidobacter piscolens (I). ND indicates not detected. The numbers at risk are presented under the survival curves. J HR of candidate prognostic species. Color and size indicate the number of significant discrimination in both discovery and test sets by univariate log-rank test and multivariate Cox model, respectively

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Microbiome

ISSN: 2049-2618

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