Fig. 6From: Deficiency of exchange protein directly activated by cAMP (EPAC)-1 in mice augments glucose intolerance, inflammation, and gut dysbiosis associated with Western dietGraphical abstract. This figure highlights the major differences in the baseline GM composition and WD-induced alterations in the GM composition, gut permeability, and inflammation between WT, Epac1–/– and Epac2–/– mice. Statistically significant differences vs. corresponding WT mice are highlighted in redBack to article page