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Fig. 4 | Microbiome

Fig. 4

From: Selected commensals educate the intestinal vascular and immune system for immunocompetence

Fig. 4

Commensal bacteria initiate gene expression of vascular and immune networks. A–C Volcano plot and STRING analysis showing fold change of gene expression in whole colon of GF and OMM12 mice (B). STRING analysis for significantly upregulated transcripts in the colon of GF (A) and OMM12 mice (C). D Heat map of differentially expressed gene clusters in OMM12 and OMM12 + MC2 at indicated time points after MC2 addition, log2-fold change ≥ 1; p-adj < 0.05. n = 4 biological replicates per group. E Principal component analysis of colonic gene expression in differently colonized mice. The axes correspond to principal component 1 (x-axis) and 2 (y-axis)

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