Fig. 7
Distribution of metabolic modules and genes in bacterial and archaeal genomes derived from marine hydrothermal systems and terrestrial hot springs. The available genomes of cultured organisms were downloaded from the IMG database and were searched against metagenomic studies to finally obtain the habitat of specific microbial genus. Organisms are colored by taxonomic classification (see legend). The metabolic and functional genes included carbon metabolism (C), terminal oxidase (O2), sulfur metabolism (S), nitrogen metabolism (N), and hydrogen oxidation (H2). Habitat types of strains are indicated by different shapes, and the number of sequenced complete genomes is shown in brackets. Genes encode the complete enzyme and all enzymes of the pathway, respectively, show the presence of corresponding functions and pathways in the genome. The frequency of occurrence of various functions of interest for each genus is shown with squares of proportional size. Bootstrap node supports ≥ 50 are denoted by a black dot, the scale bar at the bottom indicates 20% sequence divergence. CBB, Calvin-Benson-Bassham cycle; WL, Wood-Ljungdahl pathway; 3HP/4HB, 3-hydroxypropionate/4-hydroxybutyrate; DC/4HB, dicarboxylate/4-hydroxybutyrate cycle; fdh, formate dehydrogenase; cydAB, cytochrome bd quinol oxidase; ccoNOP, cytochrome cbb3 oxidase; coxABC, aa3-type cytochrome c oxidase; QoxABC, the ubiquinol-dependent cytochrome ba3 oxidase; sqr, sulfite:quinone oxidoreductase; fccAB, flavocytochrome c sulfide dehydrogenase; sox, sox multienzyme system; psrA, polysulfide reductase subunit A; hyd, sulfhydrogenase; sor, sulfur oxygenase/reductase; napAB, dissimilatory nitrate reductase; narGHI, dissimilatory nitrate reductase; nasA, assimilatory nitrate reductase catalytic subunit; narB, ferredoxin-nitrate reductase. For details on functional genes, see supplementary Tables S9 and S10