Fig. 8From: Functional changes in the oral microbiome after use of fluoride and arginine containing dentifrices: a metagenomic and metatranscriptomic studyEffects of fluoride and fluoride + arginine on arginine metabolism. The enzymatic reactions and genes responsible for arginine biosynthesis, arginine degradation through citrulline (arginolytic pathway, ADS), or arginine conversion into agmatine and its further degradation (agmatine deiminase system, AgDS) are plotted. Those genes over-represented or over-expressed after fluoride treatment are colored in orange whereas those that were over-represented or over-expressed after fluoride + arginine treatment are colored in greenBack to article page