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Table 1 Characteristics of infant cohorts and samples used in this study

From: Capturing the antibiotic resistome of preterm infants reveals new benefits of probiotic supplementation

 

NS preterm (n = 13)

PS preterm (n = 8)

p-value

Gestational age at birth, weeks

27.49 ± 2.03

28.14 ± 1.54

0.47

Probiotic exposure, weeks

0.00

8.27 ± 3.19

< 0.0001

Antibiotic exposure during sample collection (types and number of infants exposed)

Amo(1), Amp(13), Az(2), Cefa(3), Cefo(5), Cefu(1), Cl(5), G(13), Mer(2), Met(1), T(1), V(5)

Amp(6), Cefa(1), Cefo(2), Cl(3), G(6), Met(2), V(1)

N/A

Antibiotic exposure, weeks

1.98 ± 1.83

1.11 ± 1.20

0.20

Inhospital sample, weeks in PMA (N)

37.20 ± 3.80 (12)

37.86 ± 1.69 (3)

0.66

Visit 1 sample, weeks in PMA (N)

41.96 ± 2.25 (10)

42.63 ± 1.69 (8)

0.52

Visit 2 sample, weeks in PMA (N)

46.83 ± 1.75 (9)

46.43 ± 0.50 (5)

0.90

Visit 3 sample, weeks in PMA (N)

52.29 ± 2.45 (7)

54.21 ± 1.85 (6)

0.18

Visit 4 sample, weeks in PMA (N)

62.46 ± 2.56 (10)

59.68 ± 0.62 (4)

0.07

  1. PMA is the postmenstrual age in weeks, and SD is the standard deviation. The data are presented as mean ± SD. P-values < 0.05 using Student’s t-test or Mann-Whitney were considered to be statistically significant