Fig. 4

Unique ARGs, mechanisms, and families in preterm infants up to 5 months of age. Reads were mapped to CARD using bowtie2, and ARGs with at least 100 reads were reported. The data presented is for all preterm infants at all visits. A) The number of unique ARGs identified in each infant. Significant differences are denoted by a line and asterisk(s) above the groups that were compared (P = 0.0052 for visit 1, P = 0.0144 for visit 4). B) The number of ARGs identified in each infant group classified by resistance gene mechanism. The number of infant samples included in each is shown next to the sample type (NS = non-probiotic-supplemented preterm, PS = probiotic-supplemented preterm). C) A selected subset of detected AMR gene families in preterm infants. A teal box indicates that at least one gene from that AMR gene family was identified in any of the infants at that time-point