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Table 2 Influence of diet, AGPs, and combined treatment (“interaction” column) on microbiome structure as measured by PERMANOVA using weighted UniFrac distances

From: Systematic profiling of the chicken gut microbiome reveals dietary supplementation with antibiotics alters expression of multiple microbial pathways with minimal impact on community structure

GI site

Time

Diet (Accounting for AGPs)

AGPs (Accounting for diet)

Interaction

  

R2

p-val

R2

p-val

R2

p-val

PERMDISP

Gizzard

D10

0.779

***

0.008

0.444

0.015

0.282

0.622

D24

0.325

***

0.032

0.525

0.127

*

0.136

D40

0.741

***

0.014

0.332

0.012

0.383

0.475

Duodenum

D10

0.121

*

0.227

**

0.052

0.229

0.16

D24

0.105

0.169

0.024

0.856

0.023

0.863

0.988

D40

0.064

0.218

0.125

*

0.037

0.637

**

Jejunum

D10

0.404

***

0.085

0.085

0.034

0.356

0.536

D24

0.014

0.897

0.05

0.582

0.079

0.336

0.7332

D40

0.053

0.386

0.049

0.442

0.035

0.67

0.363

Ileum

D10

0.297

***

0.202

**

0.098

*

0.547

D24

0.187

**

0.024

0.808

0.074

0.218

0.81

D40

0.308

***

0.025

0.609

0.029

0.529

0.182

Ceca

D10

0.13

0.052

0.04

0.486

0.085

0.141

0.941

D24

0.249

**

0.066

0.229

0.043

0.461

**

D40

0.105

**

0.136

***

0.077

*

0.066

Colon

D10

0.118

0.054

0.099

0.101

0.039

0.549

0.97

D24

0.106

0.206

0.034

0.752

0.12

0.164

0.89

D40

0.113

0.053

0.1

0.075

0.035

0.583

0.737

  1. PERMDISP displays p-values as calculated through the PERMDISP test. Statistical significance is represented by the following: *p < 0.05; **p < 0.01; ***p < 0.001