Fig. 4From: Colistin-degrading proteases confer collective resistance to microbial communities during polymicrobial infectionsAntibacterial efficacy of colistin influenced by Cdp-producing S. maltophilia strains during Drosophila coinfection. Antibacterial efficacy of colistin was determined by the survival rate of Drosophila animals infected by P. aeruginosa PA14. S. maltophilia cells (strains Col1, Col2, and Col3) were coinfected with P. aeruginosa as described in the “Methods” section. The infected flies were fed with either 1 mg/mL colistin, and their survival rates were determined over time. The dotted lines represent the time required to reach 50% mortality. The statistical significance based on a log-rank test is indicated (*p = 0.0142; **p = 0.0058). Closed and open symbols indicate animals treated with and without colistin, respectivelyBack to article page