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Fig. 2 | Microbiome

Fig. 2

From: Microbial risk score for capturing microbial characteristics, integrating multi-omics data, and predicting disease risk

Fig. 2

The optimal p value thresholds by P+T method for including taxa in MRSα, MRSwS, and MRSunwS, separately, using the metagenomic data in the NYULH COVID-19 cohort. Specifically, given a cut-off, the taxa with p values less than the cut-off were selected and defined as a sub-community. The p values were obtained by ANCOM-BC method. The leave-one-out CV was used for the predictions. MRSα: the negative alpha diversity (Shannon index) was calculated for each sample on the selected sub-community; MRSwS: the weighted sum of relative abundances of the selected taxa with the weights being the coefficients estimated from the ANCOM-BC log-linear model; MRSunwS: the sum of relative abundances of the selected taxa

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