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Fig. 5 | Microbiome

Fig. 5

From: Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate

Fig. 5

Probiotic intervention with Odoribacter laneus has no effect in Sucnr1 knock-out mice. Weight evolution (a), food intake (b), and fasted serum succinate levels (c) of C57BL/6 wild type (WT) and Sucnr1 knock-out (KO) mice treated with O. laneus. Glucose (d) and insulin (e) tolerance tests of WT and Sucnr1 KO mice before and after probiotic treatment. mRNA expression levels of inflammatory genes in the scWAT, vWAT, liver, and intestine (f) (n = 7–8). Data are presented as mean + s.e.m. *p < 0.05; (unpaired t-test and two-way ANOVA)

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Microbiome

ISSN: 2049-2618

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