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Fig. 3 | Microbiome

Fig. 3

From: Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate

Fig. 3

Probiotic intervention with Odoribacter laneus depletes serum succinate and moderates inflammation in db/db mice. Effect of different probiotic interventions on body weight (a), food intake (b), and fasted serum succinate levels (c) (n = 8–10). Principal component analysis and average phylum, family, genera, and species abundance of the 10 more abundant taxa in the cecum of db/db mice treated with vehicle or O. laneus (d) (n = 15). mRNA expression levels of inflammatory genes in the scWAT, vWAT, liver, and intestine (e) (n = 7–10). Data are presented as mean + s.e.m. *p < 0.05; **p < 0.01; ***p < 0.001 (unpaired t-test)

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