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Fig. 6 | Microbiome

Fig. 6

From: Gut dysbiosis promotes prostate cancer progression and docetaxel resistance via activating NF-κB-IL6-STAT3 axis

Fig. 6

Clinical characteristics and gut microbiota profile in patients. A, B Shannon and Simpson indices, and cluster dendrogram and principal co-ordinates analysis (PCoA) of weighted_unifrac in three groups. C Composition of gut microbiota community (top 10) at the phylum level, and the distribution of Proteobacteria in three groups. D Correlation analysis between plasma IL6 level and the relative abundance of Proteobacteria in patients (n = 20). E ROC curves for prostate cancer vs BPH or non-metastatic prostate cancer vs metastatic prostate cancer. PSA level was used as a standard predictive marker. ROC values were conducted by MedCalc version 20. Statistical significance was assessed by Tukey-HSD and LSD in one-way ANOVA. *p < 0.05, **p < 0.01, ***p < 0.001

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