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Fig. 1 | Microbiome

Fig. 1

From: Gut dysbiosis promotes prostate cancer progression and docetaxel resistance via activating NF-κB-IL6-STAT3 axis

Fig. 1

Antibiotic exposure promoted prostate cancer growth. A Flowchart of gut dysbiosis murine model establishment. B Images for mouse with subcutaneous tumor, tumors, and comparison of volume (mm3) and weight (g) for tumors in the Abx and NC group (n = 5). C Images for the mouse with orthotopic tumor (including section for HE staining, scale bar, 50 μm), tumors, and comparison of volume and weight for tumors in the Abx and NC group (n = 5). D Flowchart of FMT processing on mice. E Images for subcutaneous tumors and comparison of volume and weight for tumors in the FMT-Abx and FMT-NC group (n = 5). F Immunohistochemistry of tumor tissues for Ki-67-positive cell in the Abx and NC or the FMT-Abx and FMT-NC group (scale bar, 50 μm). Statistical significance was assessed by unpaired Student’s T-test. *p < 0.05, **p < 0.01, ***p < 0.001

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