Gut metabolites predict Clostridioides difficile recurrence

Microbiome

Table 1 Participant demographic and clinical data

	Recurrers N = 19	Non-recurrers N = 34	P value
Demographic data
Race
Black	1	7	0.36
Hispanic	3	2
White	15	25
Sex
Male	5	13	0.55
Female	14	21	0.55
Age
Mean	57.2 ± 17.2	58.4 ± 14.3	0.7
Range	(22, 93)	(30, 87)	0.7
Clinical data
Body-mass index (BMI)
Mean	28.3 ± 6.9	29.2 ± 9.3	0.87
Range	(20.1, 45.1)	(19.4, 66.7)	0.87
Test used for diagnosis
PCR	4	17	0.046
EIA toxin	15	17	0.046
Initial treatment antibiotic used
Vancomycin	11	27	0.12
Metronidazole	8	7	0.12
Prior PPI use
No	11	17	0.77
Yes	8	17	0.77

Statistical testing was performed using Fisher’s exact test for binary variables, the chi-squared test for categorical variables, and the Wilcoxon rank-sum test for continuous variables
PCR Polymerase chain reaction, GDH Glutamate dehydrogenase, PPI Proton-pump inhibitor

ISSN: 2049-2618