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Table 1 Shared DMRs between F1 and F2 generations are likely the result of intergenerational epigenetic inheritance

From: Early life microbial exposures shape the Crassostrea gigas immune system for lifelong and intergenerational disease protection

Day 10 hyper-methylation
  F1 ME-induced DMRs (n = 2482) F1 randomly generated DMRs (n = 2482)
F2 ME-induced DMRs (n = 1230) 48.0 ± 17.9 7.20 ± 2.7
Day 10 hypo-methylation
  F1 ME-induced DMRs (n = 1843) F1 randomly generated DMRs (n = 1843)
F2 ME-induced hypo-DMRs (n = 4301) 120.0 ± 27.8 18.2 ± 4.2
Day 120 hyper-methylation
  F1 ME-induced DMRs (n = 2040) F1 randomly generated DMRs (n = 2040)
F2 ME-induced DMRs (n = 2550) 147.0 ± 38.5 14.8 ± 3.9
Day 120 hypo-methylation
  F1 ME-induced DMRs (n = 2945) F1 randomly generated DMRs (n = 2945)
F2 ME-induced DMRs (n = 2657) 252.0 ± 48.1 27.6 ± 5.3