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Table 1 Shared DMRs between F1 and F2 generations are likely the result of intergenerational epigenetic inheritance

From: Early life microbial exposures shape the Crassostrea gigas immune system for lifelong and intergenerational disease protection

Day 10 hyper-methylation

 

F1 ME-induced DMRs (n = 2482)

F1 randomly generated DMRs (n = 2482)

F2 ME-induced DMRs (n = 1230)

48.0 ± 17.9

7.20 ± 2.7

Day 10 hypo-methylation

 

F1 ME-induced DMRs (n = 1843)

F1 randomly generated DMRs (n = 1843)

F2 ME-induced hypo-DMRs (n = 4301)

120.0 ± 27.8

18.2 ± 4.2

Day 120 hyper-methylation

 

F1 ME-induced DMRs (n = 2040)

F1 randomly generated DMRs (n = 2040)

F2 ME-induced DMRs (n = 2550)

147.0 ± 38.5

14.8 ± 3.9

Day 120 hypo-methylation

 

F1 ME-induced DMRs (n = 2945)

F1 randomly generated DMRs (n = 2945)

F2 ME-induced DMRs (n = 2657)

252.0 ± 48.1

27.6 ± 5.3