Fig. 5
From: Gut microbiome mediates the protective effects of exercise after myocardial infarction
3-HPA and 4-HPA are identified to be involved in the protection of running in MI. OPLS-DA Model Discrimination based on metabolic profiles in fecal samples. A The relative abundance of each metabolite classes in different groups (n = 10:10:10:10). B The abundance of phenols in different groups. C Volcano plot of univariate statistics across Sham + control group and MI + control group. D Volcano plot of univariate statistics across Sham + control group and Sham + Run group. E Pathway analysis bubble plot by mmu set in MI + Control vs MI + Run. F Network for statistically significant changed pathways in MI + control vs. MI + Run. G The relationship between metabolites and the top 50 genera in four groups was estimated by Spearman’s correlation analysis. Those with low correlated (|r|< 0.1) were not shown. Genera and cardiac function index were distinguished as positive (red) and negative (blue) correlation. *p < 0.05; **p < 0.01; ***p < 0.001