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Fig. 4 | Microbiome

Fig. 4

From: Phylogeny-guided microbiome OTU-specific association test (POST)

Fig. 4

ROC curves of simulation A with large OTU effect size (top row) and small OTU effect size (bottom row) for POST, Single-OTU test (SO), TreeFDR (TF), DESeq2 (DE), ANCOM-BC (AB), LinDA (DA), and Wilcoxon rank-sum test (WR) under the 5 causal scenarios. Scenarios 1 to 3 consider larger “causal hubs,” each containing about 7–10 causal OTUs; scenario 4 considers smaller causal hubs of 2–3 causal OTUs; scenario 5 considers causal OTUs with random positions in the phylogenetic tree

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