Fig. 5

FMT alleviates depressive-like behaviors and cognitive decline post BCCAO. A Sucrose preference test. B–G Open-field test: B The total distance traveled by rats in the open-field test. C The frequency of grid-crossing. D The mean traveling speed. E Time spent in the outer area. F Distance traveled in the outer area. G Representative traces in the open-field test. Circle dot: start position; square dot: end position. H, I Duration of immobility and representative traces in the tail suspension test (H) and forced swim test (I). J-L Morris water maze test: J Time spent in and K frequency of visits to the quadrant where the platform was previously located. L Representative traces in the spatial probe test (the platform was previously located in the center of quadrant IV). Circle dot: start position; square dot: end position. The data represent the mean ± SEM (n = 10 S+FMT(B) and S+FMT(S), n = 14 B+FMT(B) and B+FMT(S)). p < 0.05 was set as the threshold for significance. * p < 0.05, ** p < 0.01, *** p < 0.001 compared to the S+FMT(B) group. ^&&&p < 0.001 compared to the S+FMT(S) group. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 compared to the B+FMT(B) group