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Fig. 4 | Microbiome

Fig. 4

From: The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids

Fig. 4

Fecal microbiota transplantation successfully establishes a varied gut microbiota profile. A Timeline of fecal microbiota transplantation (FMT) from BCCAO or sham animals to recipient rats (Blue arrows, FMT using fecal supernatant from BCCAO rats. Red arrows, healthy FMT using fecal supernatant from sham rats). B, C Comparison of the Chao1 index (B) and Shannon index (C) among the four groups (n = 10/group). D PCoA plot established based on the unweighted UniFrac distance (n = 10/group). E, F Representation of bacterial profiles in sham (E) and BCCAO (F) rats after receiving FMT by linear discriminant analysis coupled with effect size (n = 10/group). S+FMT(B), sham rats received BCCAO-rat-derived fecal microbiota transplantation. S+FMT(S), sham rats received sham-rat-derived fecal microbiota transplantation. B+FMT(B), BCCAO rats received BCCAO-rat-derived fecal microbiota transplantation. B+FMT(S), BCCAO rats received sham-rat-derived fecal microbiota transplantation. The data represent the mean ± SEM. p < 0.05 was set as the threshold for significance. *** p < 0.001 compared to the S+FMT(B) group. ###p < 0.001 compared to the B+FMT(B) group

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Microbiome

ISSN: 2049-2618

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