Fig. 11From: The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acidsA schematic diagram for this study. Bidirectional communications exist between the brain and the gut, with the involvement of gut microbiota through fermented metabolites such as short-chain fatty acids (SCFAs). Brain injury caused by chronic hypoperfusion induces gut dysbiosis, accompanied with decreased fermentation products. Restoring gut microbiota through fecal microbiota transplantation (FMT) alleviates disrupted gut function, neuronal apoptosis, and neuroinflammationBack to article page