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Fig. 4 | Microbiome

Fig. 4

From: A mouse model of occult intestinal colonization demonstrating antibiotic-induced outgrowth of carbapenem-resistant Enterobacteriaceae

Fig. 4

Microbiota gene functions related to mRNA degradation predict nonsusceptibility to K. pneumoniae outgrowth. a K. pneumoniae CFU for vancomycin-induced outgrowth in a repeat experiment using the design shown in Fig. 2a. Outgrowth and no-outgrowth were evenly divided post-antibiotic (N=14 each). b ROC curve for lasso machine learning model predicting susceptibility status at day 7. ROC receiver operating characteristic, AUC area under the curve. c Interpretation of the lasso machine learning model showing feature effect sizes and robustness, heatmap of top selected features, and gene names and functions

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