Table 1 Data on the administered antibiotics and their relationship with the PM2.5 resistome in the inpatient building
Antibiotic consumption | Agy | β-lactams | FQs | Gypt | MLs | TCs | |||
|---|---|---|---|---|---|---|---|---|---|
Aminoglycosides | Broad-spectrum | Carbapenems | Cephalosporins | Fluoroquinolones | Glycopeptides | Macrolides | Tetracyclines | ||
#DDDs (monthly basis) | Summer | 1740±280 | 4830±583 | 1680±73.3 | 13200±1310 | 15500±1330 | 365±55.8 | 8900±1100 | 2620±1100 |
19700±746 | |||||||||
Winter | 1470±173 | 4350±176 | 1630±132 | 12600±748 | 17400±713 | 345±50.2 | 7910±1100 | 3050±541 | |
18600±549 | |||||||||
#DDDs/patient (monthly basis) | Summer | 49.4±5.5 | 7.61±2.52 | 5.88±0.19 | 6.94±1.10 | 19.1±1.32 | 3.71±0.60 | 19.7±1.27 | 112±1.86 |
6.92±1.95 | |||||||||
Winter | 50.7±3.5 | 8.10±0.21 | 5.87±0.73 | 7.48±0.44 | 19.10±0.38 | 3.49±0.45 | 23.3±3.01 | 136±28.3 | |
7.42±0.29 | |||||||||
Correlations with corresponding ARGs† | PDDDs = 0.35 PIntensity = 0.50 | PDDDs = 0.65 *PIntensity = 0.02 (RIntensity = − 0.90) | PDDDs = 0.13 PIntensity = 0.80 | PDDDs = 0.42 PIntensity = 0.51 | PDDDs = 0.71 PIntensity = 0.56 | PDDDs = 0.41 PIntensity = 0.29 | PDDDs = 0.91 PIntensity= 0.71 | PDDDs = 0.56 PIntensity = 0.42 | |
PDDDs = 0.56; PIntensity=0.49 | |||||||||
Correlations with corresponding PARB‡ | PDDDs = 0.11 PIntensity = 0.51 | PDDDs = 0.65 *PIntensity = 0.0043 (RIntensity = − 0.95) | PDDDs = 0.25 PIntensity = 0.79 | PDDDs = 0.41 PIntensity = 0.47 | *PDDDs = 0.04 (RDDDs = − 0.83) PIntensity = 0.08 | PDDDs = 0.10 *PIntensity = 0.05 (RIntensity = 0.79) | PDDDs = 0.32 PIntensity = 0.39 | PDDDs = 0.31 *PIntensity = 0.05 (RIntensity = 0.81) | |
PDDDs = 0.48; PIntensity = 0.07 | |||||||||