Fig. 5

Circulating pro-inflammatory mediators are reduced at W12 in subjects following HAMSAB supplementation. A Serum IL-8, MIP1a, and bFGF concentrations detected by multiplex assay. Overall significance determined by GEE and pairwise differences between timepoints by estimated marginal means. Box plots show mean and upper and lower quartile ranges. B Hierarchical clustering of genes from fatty acid metabolism KEGG pathway gene set and from oxidative phosphorylation KEGG pathway gene set at baseline and 6 weeks of HAMSAB supplementation (FDR = 0.015 and 0.002, respectively). Columns represent individual subjects and rows represent individual genes in the pathway