Table 4 Fixed effects in linear mixed effects model stratified by matched pair of features associated with bacterial density (log 16S copies/specimen)

Piperacillin-tazobactam

− 1.84 (− 3.26 to − 0.42)

0.017*

Age (decade)

0.43 (0.04–0.83)

0.043*

Charlson comorbidity index

0.45 (0.16–0.74)

0.004*

SOFA Score

0.07 (− 0.13–0.27)

0.51

VRE colonization

− 0.073 (− 1.18–1.06)

0.90

 Cardiopulmonary disorder

0.67 (− 5.421–6.707)

0.84

 Neurologic abnormality

2.41 (− 4.534–9.273)

0.52

 Trauma

1.35 (− 5.104–7.798)

0.70

 Sepsis syndrome

1.45 (− 4.582–7.428)

0.65

 Non-infectious transplant complication

− 0.53 (− 7.275–6.276)

0.89

 Gastrointestinal abnormality

2.30 (− 3.944–8.433)

0.49

 Complications of chemotherapy

0.40 (− 5.607–6.357)

0.90