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Fig. 4 | Microbiome

Fig. 4

From: The bacterial density of clinical rectal swabs is highly variable, correlates with sequencing contamination, and predicts patient risk of extraintestinal infection

Fig. 4

The bacterial density of rectal swabs is strongly associated with piperacillin-tazobactam use. Bacterial density of rectal swabs was compared with clinical features and exposures using multivariable linear mixed-effect regression, stratified by matched case/control pair. Piperacillin-tazobactam exposure was associated with a 1.8 log fold decrease in bacterial density (β = − 1.83, p = 0.017). Bacterial density was positively correlated with patient age and medical comorbidities (as described by the Charlson comorbidity score) (increase in decade of age β = 0.43, p = 0.03; Charlson comorbidity score β = 0.45, p = 0.0040)

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