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Fig. 3 | Microbiome

Fig. 3

From: Ageing and rejuvenation models reveal changes in key microbial communities associated with healthy ageing

Fig. 3

Rejuvenation procedure restores age-dependent alteration of intestinal function and inflammation. a Representative PAS-stained pictures (left panel) and mucus-containing goblet cell density in the colon (right panel), Scale bar 50 μm. b Circulating plasma LPS levels measured after 6 weeks of each experiment. c Gene expression of intestinal stem cell markers in the colon. All data are presented as means ± SEMs (*P < 0.05, two-tailed Student’s t test). Co-Y young mice from co-housing experiments, Co-A aged mice from co-housing experiments, Hetero-Y young mice from heterochronic pairs, Hetero-A aged mice from heterochronic pairs, Iso-Y young mice from isochronic young pairs, Iso-A aged mice from isochronic aged pairs, iv 16 (Y→Y) young mice treated with serum isolated from young mice by intravenous injection into the tail vein 16 times, iv 16 (Y→A) aged mice treated with serum isolated from young mice by intravenous injection into the tail vein 16 times

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