Fig. 3
From: Disentangling environmental effects in microbial association networks
EnDED methods overview. EnDED is an implementation of four methods aiming to determine whether an edge between two microorganisms is indirect through the action of an environmental factor. The four methods are sign pattern, overlap, interaction information, and data processing inequality (see “Methods” section). Each method can be used individually or in combination. Here, we show the intersection combination approach, i.e., only if all methods classify an edge as indirect, it is removed from the network. Otherwise, the edge is classified as not indirect and kept in the network