Fig. 2
From: Blockage of bacterial FimH prevents mucosal inflammation associated with Crohn’s disease
Fecal microbial composition of patients with CD is characterized by a blooming of Enterobacteriaceae. a, b Top blooming species by percentage of patients with CD in Cohort 1 (a) and Cohort 2 (b), for whom a tenfold increase has been observed compared with mean relative abundance in HV. Are represented only the species with at least 20% of patients in blooming either in Cohort 1 or in Cohort 2. Note the presence of 4 Enterobacteriaceae among the top 5 species. c Relative abundance of Enterobacteriaceae spp in HV and patients with CD from Cohort 1 and Cohort 2. d Relative abundance of Enterobacteriaceae spp in HV, active and quiet patients with CD from Cohort 1 and Cohort 2. Patients with CD were considered in an active phase of the disease when HBI > 4 and in a quiet phase when HBI ≤ 4. Bars represent the median of all points. Nonparametric Mann–Whitney U test was used to identify the statistically significant differences between groups. (*P < 0.05, ***P < 0.0005, ****P < 0.0001)