Fig. 6From: Reduced B12 uptake and increased gastrointestinal formate are associated with archaeome-mediated breath methane emission in humansMetabolic network of key-stone taxa in LE (left) and HE (right) microbiomes. Information on the metabolic substrates and products were derived from literature information [52,53,54]: Lines with arrows, connecting taxa with metabolites, indicate uni-directional (grey) or bi-directional (pink) consumption and/or production. Metabolites measured in stool samples (via metabolomics; this work) are indicated by arrows in brackets following the metabolite name; respective increase (↑) or decrease (↓) of the median by >5% is displayed. For example, a substantially (>5%) increased amount of acetate, propionate and formate was measured in samples from high-methane emittersBack to article page