Fig. 5

In vivo depletion of sorbitol by sorbitol eaters. a Heat map showing growth of individual Clostridia and Erysipelotrichia isolates on no carbon defined media (NCDM) supplemented with the indicated sugars. b, c Conventional C57BL/6 J mice were mock treated or treated with a single dose of streptomycin and received drinking water supplemented with or without 5% sorbitol. b The concentration of sorbitol in ceca contents was measured by ELISA 3 days after streptomycin treatment. c One day after streptomycin treatment, mice were mock inoculated or inoculated with A. caccae (designated “strain 9” in panel a). The concentration of sorbitol in cecal contents was measured by a colorimetric assay 3 days after streptomycin treatment. LOD, limit of detection; ****, P < 0.0001