Fig. 1From: The metabolic footprint of Clostridia and Erysipelotrichia reveals their role in depleting sugar alcohols in the cecumStreptomycin treatment alters the mouse cecal metabolome, characterized by an increase in carbohydrates. Mice were mock-treated (n = 12) or received a single dose of streptomycin (n = 8) and the cecal metabolome was analyzed 3 days later (mice of each group were housed in three different cages each). a PCA plot showing variation of the mouse cecal metabolome by treatment group. b Bar plot displaying the number of significantly increased and decreased metabolites by metabolite class in streptomycin-treated mice relative to mock-treated mice (FDR corrected P value =  < 0.05). c Volcano plot of metabolites colored by class. Metabolites with a positive fold-change value increased with streptomycin treatment while metabolites with a negative-fold change value decreased with streptomycin treatment. The dashed line is set at an FDR corrected P value of 0.05. d Bar plot displaying the number of differentially significantly increased and decreased carbohydrates by metabolite subclass in streptomycin-treated mice relative to mock-treated mice (FDR corrected P value ≤ 0.05)Back to article page