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Fig. 1 | Microbiome

Fig. 1

From: The metabolic footprint of Clostridia and Erysipelotrichia reveals their role in depleting sugar alcohols in the cecum

Fig. 1

Streptomycin treatment alters the mouse cecal metabolome, characterized by an increase in carbohydrates. Mice were mock-treated (n = 12) or received a single dose of streptomycin (n = 8) and the cecal metabolome was analyzed 3 days later (mice of each group were housed in three different cages each). a PCA plot showing variation of the mouse cecal metabolome by treatment group. b Bar plot displaying the number of significantly increased and decreased metabolites by metabolite class in streptomycin-treated mice relative to mock-treated mice (FDR corrected P value =  < 0.05). c Volcano plot of metabolites colored by class. Metabolites with a positive fold-change value increased with streptomycin treatment while metabolites with a negative-fold change value decreased with streptomycin treatment. The dashed line is set at an FDR corrected P value of 0.05. d Bar plot displaying the number of differentially significantly increased and decreased carbohydrates by metabolite subclass in streptomycin-treated mice relative to mock-treated mice (FDR corrected P value ≤ 0.05)

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