Fig. 10

EGCG-FMT promoted the enrichment of SCFAs-producing bacteria and production of SCFAs. a α-diversity upon oral therapy represented by the Sobs index. b PCoA plots upon FMT or SFF assessed by PERMANOVA analysis. The relative abundance of fecal bacterial phyla (c), and genera (d) presented in 99.5% of the community. e Analysis of differences in the microbial taxa shown by LEfSe (LDA coupled with effect size measurements) upon FMT. Concentrations of fecal acetate (f), propionate (g), and butyrate (h) upon FMT. Data were presented as means ± SEM (n = 8 per group). Statistical significance was determined using one-way ANOVA, followed by Tukey test. *P ≤ 0.05, ***P ≤ 0.001. i Spearman correlation between intestinal microbiota and anti-inflammatory or anti-oxidative parameters in DSS-treated mice in response to FMT or SFF. The red color denotes a positive correlation, while blue color denotes a negative correlation. The intensity of the color is proportional to the strength of Spearman correlation. *P ≤ 0.05, ***P ≤ 0.001