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Fig. 5 | Microbiome

Fig. 5

From: Review: microbial transformations of human bile acids

Fig. 5

Potential increased diversity of host BA pool as a result of MCBA production. With the current understanding of BA metabolism, A primary BAs CA and CDCA are known to be conjugated in the liver to taurine and glycine to form B GlyCA, TaurCA, GlyCDCA, and TaurCDCA, completing the pool of primary human BAs. In light of recent research, CA is also known to be conjugated by gut microbes to form C PheCA, LeuCA, and TyrCA [5]. Expanding the potential library of microbially conjugated BAs by including the remaining amino acids conjugates for D CA and E CDCA increases the diversity of human BAs over 5-fold for these backbones alone

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