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Fig. 4 | Microbiome

Fig. 4

From: Novel insights into the genetically obese (ob/ob) and diabetic (db/db) mice: two sides of the same coin

Fig. 4

Different subcutaneous adipose tissue features between ob/ob and db/db mice. (a) mRNA expression of SAT immune cells markers measured by RT-qPCR. (b) Representative pictures of F4/80 staining in SAT. Scale bar, 100 μm; magnification, × 20. Arrowheads point to crown-like structures. (c) mRNA expression of SAT receptors and inflammatory cytokines markers measured by RT-qPCR. (d) mRNA expression of SAT lipid metabolism and adipogenesis markers measured by RT-qPCR. Green: CT ob lean mice, red: ob/ob mice, blue CT db lean mice, and violet: db/db mice. Data are presented as the mean ± s.e.m, *P < 0.05, **P < 0.01, ***P < 0.001 (n = 8–10). For the mRNA expression, relative units were calculated versus the mean of the CT ob mice values set at 1. Data were analyzed by one-way ANOVA followed by Tukey’s post hoc test

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