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Fig. 6 | Microbiome

Fig. 6

From: Roux-en-Y gastric bypass-induced bacterial perturbation contributes to altered host-bacterial co-metabolic phenotype

Fig. 6

OPLS-DA cross-validated scores plots of faecal 1H NMR spectra of the RYGB patients from cohort 1 at pre-op, and 1–2 years post-op (A, Q2Y = 0.18; R2X = 31.8%, R2Y = 61.2%, p = 0.002), and at 2–6 months and 1–2 years post-op (B, Q2Y = 0.2; R2X = 30.7%, R2Y = 65.3%, p = 0.002). The metabolites that significantly contributed to the classification of different time points are shown in the heatmap (C). The correlation coefficient (r) was derived from OPLS-DA models and a positive correlation indicates higher relative concentrations of the metabolites in 1–2 years post-op compared to either pre-op or 2–6 months post-op. q, the corrected p values using Benjamini-Hochberg multiple test correction are shown as ‡q < 0.001, †q < 0.005, *q < 0.05. ap < 0.05 and q > 0.05. Faecal pH of the RYGB patients at pre-op, 2-6 months and 1-2 Y post-op (D)

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