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Fig. 4 | Microbiome

Fig. 4

From: Roux-en-Y gastric bypass-induced bacterial perturbation contributes to altered host-bacterial co-metabolic phenotype

Fig. 4

Trajectory PCA scores plot of serum 1H NMR spectra of RYGB patients from cohort 3 at pre-op and 1, 3, 6, 9 and 12 months post-op (A). Data are presented in mean ± SEM. The metabolites that were significantly different between pre-op and each of the post-op time points are summarized in the heatmap (B). The last two columns show the metabolite changes between pre-op and 6 months post-op in cohort 2 alone and in combined analysis of cohorts 2 and 3. The correlation coefficient (r) was derived from OPLS-DA models (Figure S6) and a positive correlation indicates higher relative concentrations of the metabolites in post-op compared to pre-op. q, the corrected p values using Benjamini-Hochberg multiple test correction are shown as *0.005 < q < 0.05. ap < 0.05 and q > 0.05

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