Fig. 5
From: A synthetic probiotic engineered for colorectal cancer therapy modulates gut microbiota
Longitudinal analyses of the gut microbiota of AOM/DSS mice treated with PP*-P8. a Changes in alpha diversity indices of microbial communities in the fecal samples. Species richness and evenness are plotted as the number of observed ASVs and inverse Simpson and Shannon indices. b Principal coordinate analysis based on Bray-Curtis dissimilarity. Each dot indicates a single sample and each group is shown in a different color. P values correspond to the permutational multivariate analysis of variance results. c Microbial composition at the family level is shown as relative abundance. Except for stage 0.5, which shows a single sample, proportions are the averages of five samples. D0, day 0