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Fig. 2 | Microbiome

Fig. 2

From: Pre-digest of unprotected DNA by Benzonase improves the representation of living skin bacteria and efficiently depletes host DNA

Fig. 2

Human DNA is efficiently depleted by the BDA approach with no impact on the microbiome profile. a DNA yields from skin mock community samples with heat-inactivated bacteria and added free DNA (hi, DNA), further supplemented with 105 PBMCs and processed either with BDA or NDA. p values were calculated using Wilcoxon-Mann-Whitney test *** p ≤ 0.001. b Percentage of reads related to humans or bacteria based on metagenomic sequencing. *** p ≤ 0.001. c Relative OTU abundance obtained from amplified 16S rRNA genes from mock community members following BDA or d NDA approaches

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Microbiome

ISSN: 2049-2618

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