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Fig. 8 | Microbiome

Fig. 8

From: Parabacteroides produces acetate to alleviate heparanase-exacerbated acute pancreatitis through reducing neutrophil infiltration

Fig. 8

Parabacteroides produced acetate to reduce neutrophil infiltration in Hpa-exacerbated acute pancreatitis. a–d WT and Hpa-Tg littermates were treated with/without P. distasonis and injected with Cn to induce AP. n = 5 individuals/group. Representative plots of flow cytometry and bar plots of neutrophils in whole blood were shown in (a) and (b), respectively; representative plots of immunohistochemistry and bar plots of neutrophils in pancreas were shown in (c) and (d), respectively. e and f WT and Hpa-Tg littermates were treated with/without acetate and injected with Cn to induce AP. n = 5 individuals/group. Representative plots of flow cytometry and bar plots of neutrophils in whole blood were shown in (e) and (f), respectively. Representative plots of immunohistochemistry and bar plots of neutrophils in pancreas were shown in (g) and (h), respectively. Data were expressed as mean ± SEM. Differences of data were assessed by ordinary one-way ANOVA or Kruskal-Wallis test depending on the sample distribution. Exact p levels were all provided. Scale bars, 200 and 50 μm, respectively. AP, acute pancreatitis; Cn, caerulein; Hpa-Tg, heparanase-transgenic; P. distasonis, Parabacteroides. distasonis; WT, wild type

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