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Fig. 7 | Microbiome

Fig. 7

From: Parabacteroides produces acetate to alleviate heparanase-exacerbated acute pancreatitis through reducing neutrophil infiltration

Fig. 7

Acetate supplementation mirrored the role of Parabacteroides in heparanase-exacerbated acute pancreatitis. a Acetate supplementation experimental design. WT and Hpa-Tg littermates received normal drinking or acetate supplementation (200 mM) for 3 weeks. After acetate supplementation, AP induction were performed. b Pancreas (g)/body weight (g) × 1‰. c Serum amylase. d Serum lipase. e Representative images of pancreatic H&E staining. f Histologic score. g Serum TNF-α measured by ELISA. h Serum IL-6 measured by ELISA. a–h n = 5 individuals/group. Data were expressed as mean ± SEM. Differences of data were assessed by ordinary one-way ANOVA. Exact p levels were all provided. Scale bars, 500 and 200 μm, respectively. AP, acute pancreatitis; Cn, caerulein; Hpa-Tg, heparanase-transgenic; WT, wild type

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