Skip to main content
Fig. 6 | Microbiome

Fig. 6

From: Parabacteroides produces acetate to alleviate heparanase-exacerbated acute pancreatitis through reducing neutrophil infiltration

Fig. 6

Parabacteroides restriction decreased acetate production in Hpa-Tg mice. a Annotation of microbial gene function of WT and Hpa-Tg mice on KEGG pathway analysis (Top 30). Analysis of 16S rRNA sequencing data from Fig. 2. n = 15 individuals/group. b SCFAs concentration from cecal content between healthy WT and Hpa-Tg littermates. n = 5 individuals/group. c SCFAs concentration from cecal content in 1490 vehicle group and P. distasonis group. n = 9 WT mice/group. d The correlation between acetate concentration and Parabacteroides abundance was analyzed using Spearman’s correlation. Five mice each in the WT and Hpa-Tg mice were included in the statistics. Data were expressed as mean ± SEM. Differences of data between two groups were assessed by Mann-Whitney test. Exact p levels were all provided. Hpa-Tg, heparanase-transgenic; KEGG, Kyoto Encyclopedia of Genes and Genomes; P. distasonis, Parabacteroides distasonis; rRNA, ribosomal RNA; SCFAs, short-chain fatty acids; WT, wild type

Back to article page