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Fig. 1 | Microbiome

Fig. 1

From: Challenges in exploring and manipulating the human skin microbiome

Fig. 1

Skin microbiota, its roles, and its relationship with the immune system. The skin microbiota is composed of bacteria, fungi, archaea, viruses, and mites (Demodex) that are related to the immune system through dialog with resident dendritic cells resulting from complement activation. a The immune system is enhanced by the quorum-sensing process between bacterial populations, which can limit the overgrowth of potential pathogens, or by the production of certain antibiotics, such as lugdunin (c). Microbiotic homeostasis is dependent on the production of antimicrobial peptides (AMPs) both by bacteria themselves and by host cells, such as keratinocytes and sebocytes (b and d).

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